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PLATELET ACTIVATING FACTOR
Descriptors Found:
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DeCS
Descriptor
English
:
Platelet Activating Factor
Descriptor
Spanish
:
Factor de Activación Plaquetaria
Descriptor
Portuguese
:
Fator de Ativação de Plaquetas
Synonyms
English
:
Acetyl Glyceryl Ether Phosphorylcholine
AGEPC
PAF-Acether
Phosphorylcholine, Acetyl Glyceryl Ether
Tree Number:
D02.033.100.291.211.500
D02.092.063.291.211.500
D02.092.877.883.333.710
D02.675.276.232.710
D10.570.755.375.760.400.985.910
D23.119.865
D23.469.050.600
Definition
English
:
A phospholipid derivative formed by PLATELETS;
BASOPHILS
;
NEUTROPHILS
;
MONOCYTES
; and
MACROPHAGES
. It is a potent platelet aggregating agent and inducer of systemic anaphylactic
symptoms
, including
HYPOTENSION
;
THROMBOCYTOPENIA
;
NEUTROPENIA
; and
BRONCHOCONSTRICTION.
History Note
English
:
1983(1979)
Allowable Qualifiers
English
:
analogs & derivatives
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
23518
Unique Identifier:
D010972
Occurrence in VHL
:
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